Medication For Autism and ADHD
Many people with autism also have ADHD, and medication for ADHD can sometimes help with the overlapping autism symptoms, such as hyperactivity and the tendency to be impulsive. However, medications can cause side effects.
Research is needed to better comprehend the impact of co-occurring symptoms on the outcome of treatment. Drugs like methylphenidate (Ritalin) typically treat ADHD and may also help with autism-related symptoms that are overlapping and other anticonvulsant medications.
Medications for Inattention
Autism and attention deficit/hyperactivity disorder (ADHD), are disorders that coexist. Between 30 and 50% of those diagnosed with autism also have ADHD symptoms. This co-occurrence is clinically and epidemiologically significant, because effective treatment of the primary symptoms of both disorders enhances the ability to adapt and reduce negative coping behaviors [1, 2].
Hyperactivity, inattention, and impulsivity are all signs of ADHD. The medications used to treat symptoms of ADHD tend to reduce these symptoms and can help to improve social, academic, and behavioral outcomes in those with autism and ADHD.
In a longitudinal cohort study, researchers found that the proportion of individuals prescribed a psychotropic medication was similar for people with and without co-existing autism. The medication class and frequency of prescriptions varied between the two groups. The most commonly used medication was stimulant, followed by atomoxetine and then antipsychotics and SSRIs. In a subgroup study, people with ADHD-Combined as well as those with autism were more likely to receive ADHD medication, whereas children with ADHD-Inattentive had a lower chance to receive medication than those with autism in isolation.
Stimulants increase the levels of dopamine and norepinephrine within your brain which are neurotransmitters that are associated with motivation as well as reward, decision-making and emotional. The use of stimulants has been proven to be effective in decreasing ADHD symptoms among children with autism and ADHD. However there are some who may experience adverse reactions such as stomach problems, headaches and insomnia.
over the counter adhd medication , like Guanfacine and atomoxetine, also appear to decrease ADHD symptoms in people with autism and coexisting ADHD. Indirect evidence of low-quality suggests that Atypical antipsychotics risperidone and Aripiprazole might reduce irritability in children with ASD but further research is required to determine if this is an effect of reducing ADHD symptoms or a result of these medications on core ASD behavior.
A better understanding of co-occurring signs can help clinicians determine the best time and duration of psychosocial treatment versus pharmacological therapy, and pinpoint the crucial periods where intervention may be most effective. Improved knowledge of the co-occurring symptoms and how they interact over time will help identify optimal treatment interventions to mitigate the negative effects of ADHD symptoms on ASD fundamental functions.
Hyperactivity Meds
Although few research studies have compared psychopharmacological treatment for coexisting ADHD and autism, available data suggests that individuals with both conditions may benefit from optimal use of medication. A number of clinical trials have shown that stimulant medication (methylphenidate and atomoxetine) improve core ADHD symptoms in children and adolescents with ASD.
The same drugs have been proven to enhance social skills among those with autism. These medications are not risk-free and should only ever be prescribed by a medical professional who is knowledgeable about the risks and benefits of each drug. In addition, individual people with autism tend to react differently to each medication and some medications may cause harm in certain circumstances.
A large survey of the population revealed that two thirds (63 percent) of children aged 6-11 and 35% of youth aged 12-17 who had ADHD and autism co-occurring were taking psychotropic medications. This was similar to rates of psychiatric drugs used by children and youths with ADHD alone. The comorbid diagnosis of schizophrenia, intellectual disability, and OCD were more common among those who suffer from ADHD and ASD compared to those with ADHD alone.
This study also found that individuals with coexisting ADHD and ASD were less likely to start and continue continuous psychopharmacological treatment than those with ADHD alone. This is due to the higher rate of discontinuation in ASD patients due to adverse effects like irritability and difficulty in absorbing methylphenidate doses.
Comorbid ADHD and Autism are correlated with greater impairments than either condition on its own. Therefore it is crucial to optimize the treatment of both conditions. Research should focus on identifying the psychosocial treatments that work best for coexisting ADHD and autism. These include behavior therapy such as parent education, social skills training. These therapies have been proven to reduce disruptive behaviors associated with ADHD and autism. Future research should also examine the developmental pathways of the coexisting disorders to determine when symptoms change during development of the course and how it impacts the treatment. This research will allow us to develop more specific treatments that are suited to the specific needs of those with ADHD and ASD.
Anxiety Medications
Autism is a complex and challenging disorder that can cause difficulties in many areas, including emotions, concentration, sleep, and behaviors. While non-medicated treatment is often the first option but medication can offer relief and give parents and children the tools to help them succeed. The medicines that treat ADHD can also help people with autism cope better with anxiety and depression.
Stimulant medications can be helpful in treating "core" ADHD symptoms which affect social, behavioral and academic advancement. A better focus and ability to complete tasks can have a significant effect on writing, reading and other academic skills. Medications can bring noticeable improvements in the ability to interact with peers, and the frequency of self-injurious behavior, tantrums and aggression could decrease too.
Antidepressants may be prescribed to children with autism to reduce their irritability and improve their mood. These medications are referred to as selective serotonin reuptake inhibitors (SSRIs) and include fluoxetine. SSRIs have been proven to reduce depression, anxiety, and other conditions for those with autism, but large clinical studies are needed to confirm these effects.
Some antipsychotics, such as Risperidone and Aripiprazole are used to manage the anger, and emotional outbursts, that are common to some people with autism. FDA has not yet approved the use of these drugs to treat autism. However, they could be a useful tool for improving emotion regulation in children and adults.
Research is also underway to study how co-occurring disorders like autism and ADHD affect the trajectory of symptoms over time. A better understanding of these connections may lead to more effective pharmacological and psychological treatments.
It is important to know that medications can cause adverse effects and should be used with caution. It is also a good idea to test other options prior starting treatment with medication, especially in young children. If properly titrated, these medications can be an effective tool to improve the quality of life of those with autism and ADHD.
Treatments for Emotions
If a child diagnosed with Autism is suffering from extreme anxiety or depressive symptoms They can be so severe that they cause problems with their daily activities. In these cases, doctors might prescribe medication to help manage the emotions.

The drugs for ADHD can be used to decrease anxiety, impulsivity, and other signs of autism. These medications are usually used in combination with other behavioral therapies. A variety of medications, including SSRIs are able to relieve depression and anxiety for people with autism. Autism sufferers can be treated with other medications, such as atypical psychiatric medications and alpha-2-adrenergic antagonists.
Researchers recognize that autism and ADHD are often found together, even though they are distinct diagnoses. Around half of children diagnosed with autism display ADHD symptoms like hyperactivity and inattention. Many families are required to take medication to treat both conditions.
Adults and children suffering from ADHD and autism are treated most commonly by medication. It is not meant to cure autism, or to completely eliminate the associated behaviors. It can manage specific symptoms that make it difficult for a child to perform at school and in social situations.
Research has shown that antipsychotics with atypical properties, such as risperidone, can decrease aggression and irritability in some people with autism. These medications can also help reduce the psychotic symptoms that can be present in certain individuals with autism, such as hallucinations and delusions.
It is important to remember that the majority of the drugs that are approved by Health Canada have not been studied specifically in children or youth with autism. Instead, they have followed a standard path to being made available for sale: clinical observation in a limited number of people with positive outcomes, publication of cases, increased off-label use, open-label drug trials and then placebo-controlled controlled, randomized studies.
The most commonly prescribed medications for adults and teens who have coexisting ASD and ADHD are methylphenidate (Ritalin, Concerta, Metadate) amphetamines (Adderall, Dexedrine, Vyvanse) and atomoxetine (Strattera). These medications are also the most commonly prescribed medications for children suffering from pure ADHD. Treatments for anxiety, such as SSRIs, benzodiazepines and anti-seizure medication, haven't been extensively studied in this particular population, therefore the evidence of their effectiveness isn't as strong.